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Here’s What Makes Measles So Dangerous

Measles is one of the most contagious diseases
known to man. In fact, if someone with measles coughs in
an elevator, 90% of the people who use that elevator after will catch the disease. Unless of course you’ve been vaccinated. Then you’ll be completely fine. This is the measles virus, it’s been around
for thousands of years and has been responsible for the deaths of millions of people. Now, on the surface, measles symptoms seem
fairly innocuous. But the real damage, the damage that can lead
to death, happens on a cellular level. Hi I’m Roberto Cattaneo. I’m a Doctor of Philosophy and Professor of
Molecular Biology at the Mayo Clinic. I’m studying the measles virus since about
35 years. Measles uses the trachea
as a trampoline. It is in the ideal position in the body to
get expelled and to get aerosolized dispersed in the air in small particles very efficiently. When someone with measles coughs or sneezes,
these droplets contain the measles virus, and because measles is a respiratory disease,
all someone needs to do is breathe in that infected air in order to contract measles. Unless, of course, they’ve been vaccinated. When the measles virus reaches the lungs,
it is met by a type of white blood cell called a macrophage. Usually, macrophages seek out and destroy
dangerous pathogens like viruses. But the measles virus tricks the macrophage
into not seeing it as a danger and instead, safely transports the virus into the body’s
lymph nodes. It’s here that the virus begins to replicate
and spread throughout the entire lymphatic system. Yea, I mean the macrophages thinks to have a
system in which they basically get rid of the virus and the virus is. And measles can stay there. So not only it is invisible but it begins
to make damage to these cells. The task of these cells is also to go out and fight infection, but instead of fighting infection, they go out with the virus and distribute it to the body. Now, as the virus starts to spread, it enters
immune cells that express a protein named SLAM. These cells are “memory” immune cells,
meaning that they remember other pathogens that previously infected the host. Measles attacks and kills these SLAM-expressing
memory cells and once those memories of past infections are erased, the body will be in
a much weaker position to fight off future infections This is why measles is so deadly. But even though the virus has tricked your
immune system to helping it, that doesn’t mean your immune system has given up. Well, at some point the immune system will notice
and will secrete cytokines and attract other immune cells. So at some point the enemy will be identified
and taken care of. But for the viruses in fact it is only necessary
to get out of the host and find a new host. So it’s in fact better not to kill the host. That’s right, it’s in the best interest
of the virus not to kill you, that’s some other diseases job. The job of the measles virus is to find a
new host, which brings us to another protein the virus expresses: nectin4. And we discovered nectin 4as the epithelial receptor
or host exit receptor for measles virus. As measles spreads throughout the body, it
also enters cells that express the protein nectin4. This protein is expressed very preferentially
in the trachea. And the more the virusit replicates in the trachea,
the more cells it kills there. This dead cell build up actually causes the
human host to cough or sneeze, helping spread it into a new human host, bringing us right
back to where we started. Now, the good news is that once you get the
measles, your body learns how to defeat it and you probably won’t get it again. This is similar to how the vaccine works,
but the difference is you’re given a weaker dose, so you can become immune without getting
sick or damaging your immune cells. So the vaccine causes the host to remain immune
to measles we think for life long or almost life long time. And without measles, other diseases, the ones
that actually do the killing, have gone down. Basically the number of hospitalization has
been reduced considerably sometimes to about half for several different infectious diseases. So, if you haven’t been vaccinated… Yea, the vaccine works beautifully. maybe think about it? Measles may be the enemy of the immune system,
but researchers, including Dr Cattaneo, are working on ways to alter the measles virus
so it kills cancer cells. For me, a reason to continue study measles
is to make it into a friend, making an old enemy into a new friend by modifying it genetically.

Randall Smitham



  1. Emperor Zoditron Posted on April 30, 2019 at 10:58 pm

    Ha ha, I got immunized, suckers. Have fun with your anti-vaxx movement and natural selection.

  2. Spaghetties Posted on April 30, 2019 at 11:14 pm

    I love the vintage illustrations used!

  3. Vicky Mc Posted on April 30, 2019 at 11:17 pm

    Some of the severe complications from getting the measles virus are: pneumonia (1 in 20 kids get this), ear infections that can course permanent hearing loss (1 in 10), vision loss or blindness (2 in 1000), swelling of the brain coursing fits and mental disabilities/ or strokes (1 in 1000).
    In pregnant women it can course low birth weight, premature labour, vision loss or blindness to the baby, for the baby to have hearing loss or be deaf. Or course miscarriages and stillbirths.
    For every 1,000 children who get measles, one or two will die from it.

  4. Galactofagis Posted on April 30, 2019 at 11:50 pm

    Devil injections. Me and my children will survive with God at our sides.

  5. eXistenZ Posted on May 1, 2019 at 12:01 am

    Borat is that you

  6. Derrick cushshon Posted on May 1, 2019 at 12:20 am

    Watching this make me feel bad for all the non vaccinated kids out there…😂😂😂

  7. Rabbi Shekelstein Posted on May 1, 2019 at 1:14 am

    What the media wants you to believe
    Thanks antivaxers!
    Reality of measles outbreak
    Thanks immigrants!

  8. The 10th Man Posted on May 1, 2019 at 1:24 am

    Madagascar Measles Deaths – 1500. U.S. Measles Deaths – 0. Modern health care in the U.S. has turned Measles into a cold.

  9. Jaylen D. Posted on May 1, 2019 at 2:15 am

    didn’t the movie I Am Legend depict what happens when you try to treat cancer with measles?

  10. The sexy gaming channel Posted on May 1, 2019 at 2:34 am

    can you do a video on the grand solar minimum?

  11. billy the dead Posted on May 1, 2019 at 3:20 am

    Stupid people are going to kill us all

  12. BroTGM Films Posted on May 1, 2019 at 3:27 am

    Damn, now I wanna play PlAgUe InC.

  13. Mo'Sha Carter Posted on May 1, 2019 at 4:33 am

    It’s funny how some vaccinated parents aren’t vaccinating their vulnerable kids “for their well being”.

  14. CarlosIsDown Posted on May 1, 2019 at 4:48 am

    Ben Garrison is pro-plague

  15. Gautham e.m Posted on May 1, 2019 at 4:50 am

    I’m just waiting for the comments of non vaccinators 😂😂

  16. Patrick Roelant Posted on May 1, 2019 at 5:04 am

    why does this video feel so fast

  17. Blakk Dwight Posted on May 1, 2019 at 5:26 am

    This channel is officially a propaganda arm now!…. Pushing vaccines?! Why not just light people on fire or drive a stake through their heart? Today's vaccines are full of toxic poisons and chemicals that have NO PLACE in a human body! READ THE INSERT (IF THEY'LL EVEN GIVE IT TO YA). THE MMR KILLED MY DAUGHTER IN LESS THAN 24 HOURS!!!….. JUST DON'T!!

  18. Zarion 11 Posted on May 1, 2019 at 5:42 am

    Measles can be deadly. And vaccines are so incredible succesful, people have forgotten how deadly measles can be. Hence the rise of anti-vaxxers. My god, these anti-vaxxers have autism already.

    Not that vaccines causes autism though.

  19. Ilman Hakim Posted on May 1, 2019 at 6:22 am


  20. Zach Crawford Posted on May 1, 2019 at 7:00 am

    If measles eliminates immune "memory" does it also sometimes eliminate allergies? I'm aware that even if it did eliminate allergies. It would be a really stupid and risky way to do so but I'm curious nonetheless.

  21. Colland Posted on May 1, 2019 at 7:10 am

    Vaccines work for the most part, but saying you can't get infected if your vaccinated is just wrong. Also, sometimes, but very rarely, vaccines can cause serious problems. Some people have died from vaccines. But less then 0.1% of the time. Light side effect are more common.

  22. Alex Monreal Posted on May 1, 2019 at 7:30 am

    Anti-vaxers have left the chat.

  23. Rick White Posted on May 1, 2019 at 7:45 am

    Everybody without the vaccine shouldn't be allowed to enter a plain and the passport should be redrawn!
    I guess that would keep trump at home. That idiot is spreading stupid conspiracies about vaccines.

  24. TheyCallMeNewb Posted on May 1, 2019 at 7:54 am

    Host Julia years ago quipped "give the diseases diseases" with respect to an altered polio virus treatment for a brain tumour. Is Mayo the one looking to this?

  25. Fasin Posted on May 1, 2019 at 8:03 am

    Oh really??? At least I’m VACCINATED. 😎👍🏽👌🏽

  26. Fasin Posted on May 1, 2019 at 8:06 am

    Natural selection is in the works by killing off the antivaxers. Beautiful.

  27. Robert Muldoon Posted on May 1, 2019 at 8:19 am

    Yeah why bother with an immune system designed to combat and learn from certain exposures to viruses that has taken millions of years to evolve when you can be injected with questionable chemical cocktails designed and produced by Corporations that are Profit driven and have been proven time and time and time again to harm and even kill people yet face only minor penalties due their corrupting monetary influence on the Government 😉

  28. Retrograde Beats Posted on May 1, 2019 at 9:48 am

    Anti vaxxers : “do your research”

    Also anti vaxxers: *dies in plague

  29. pixelspring Posted on May 1, 2019 at 10:07 am

    Your initial statement , that measles has led to the deaths of millions of people is outright Blatant non factual Bullshit . This is supposed to be a fact based presentation, not a PR propaganda campaign for Merc and big pharma corps. .. millions of people used to contract the disease , resulting in little more than a few days of quarantine and without any lasting health issues whatsoever… I should know, I had the measles as a child and it really was very mild.. I've had worse flu viruses by far.. It has only been since Merc made a vaccine that they then pushed this fear porn into the public sphere… Its NOT fatal except in very VERY VERY rare cases … Perhaps with individuals with already compromised immunity.

  30. velcroman11 Posted on May 1, 2019 at 10:38 am

    Any parent that stops a child from having a vaccine should have that child removed from them. They should then be charged with child abuse and child neglect.

  31. g kx Posted on May 1, 2019 at 12:44 pm

    please get someone without a lisp to do the god damn voiceover, absolutely annoying

  32. JTheory Posted on May 1, 2019 at 1:45 pm

    Didnt like the format. enjoy seeing the presenter. favoured hosts for seeker seem to be female. show more female presenters/jounalists

  33. K Dub Posted on May 1, 2019 at 1:47 pm

    @Mentos no small pox has been eradicated worldwide, not a single case since 1977 anywhere in entire world. And polio had 33 cases worldwide out of 7 billion people, you'll get struck by lightning several times before you ever get those diseases.

  34. Shanne Kirby Sta Maria Posted on May 1, 2019 at 3:23 pm

    But what if they developed the Anticancer measles but won't work because of the vaccines?
    Im not a retard antivaxxer. Just a skin that's all

  35. Apollyon6660 Posted on May 1, 2019 at 5:02 pm

    Isn’t there currently an outbreak in America? Very dangerous to modify the virus, it might evolve and become much worse. I wish you all the best, however I would suggest working with A.I. to modify the Virus.

  36. apricotcoconut Posted on May 1, 2019 at 6:04 pm

    GMO's are so good, if they can modify measles what can possibly go wrong! And everyone here is so right! Mandate vaccines, an idea so good it has to be mandated!

  37. Michael Folino Posted on May 1, 2019 at 7:41 pm

    All the people not getting their children vaccinated should be charged with child abuse and should have their children removed from their custody. If these parents manage to fly under the radar and plan on having grandkids one day they had better start teaching their kids about the "birds and the bees" when the kids are 7-8 years old so their child can have a baby by 12-14 because old age without vaccines is around 30-40. Ugh, whatever, just thin the god damn heard of these morons as they are not needed!

  38. Max Power Posted on May 1, 2019 at 10:49 pm

    Ah more vaccine propaganda. They won't stop until the entire population is too brain damaged to resist.

  39. Mickey The maltipoo Posted on May 1, 2019 at 11:29 pm

    Natural selection at its best

  40. Mickey The maltipoo Posted on May 1, 2019 at 11:35 pm

    Who else thinks it's a bad idea to genetically modified measles

  41. Kristopher Rosales Posted on May 2, 2019 at 4:00 am

    I'm really glad we eradicated smallpox before anti vaxxers came to be

  42. Mudbone gaming Posted on May 2, 2019 at 7:30 am

    The music…….

  43. Nihal shah Posted on May 2, 2019 at 10:46 am

    Please make a video about IBS

  44. Bad Monkey Posted on May 2, 2019 at 11:41 am

    "If you haven't had the vaccine.. maybe think about".

    MAYBE?? Seriously?!

    No maybe about it. It's just about the most infectious disease known to humankind. If your child gets Measles because you didn't inoculate then when you could have its child abuse. Not just to your child, but then every single person who gets the disease because of them.

  45. Bilal Posted on May 2, 2019 at 11:44 am

    Measles trickery is on par with the Zionists

  46. Jennifer Isaacs Posted on May 2, 2019 at 2:26 pm

    Would anti vaxxers understand science of this? I guess that is like asking of flatearthers or those that believe space is fake to understand physics or math.

  47. arnuldo valez Posted on May 2, 2019 at 4:09 pm

    My brothers bad I got measles and chicken pox when child and we stayed in the house for a week until we were better. It wasn’t as bad as the media and vaccine companies say it is. I do not have any side effects from having the measles, I think vaccine companies make lots of money out of it and that’s the reason of scaring people

  48. Alaska 1429 Posted on May 2, 2019 at 10:32 pm

    1950: In the 2000s we will have flying cars

    Also 2019: The Earth is flat

  49. icy storm Posted on May 3, 2019 at 1:49 am

    OMG!!! 🙈🙉🤣🤣🤣

  50. icy storm Posted on May 3, 2019 at 1:50 am

    OMG!!! 🙈🙈🙈🙈🙉🙉🤣🔥👍😆
    "Its better not to kill the hoes!"

  51. Desolate Nation Posted on May 3, 2019 at 3:15 am

    I’m calling bullshit!! On your accent. Sounds fake, brah.

  52. myownname myownlastname Posted on May 3, 2019 at 5:22 am

    Where is the statistics comparison between the MMR vaccine side effects and the Measles illness ?

  53. Gold Leaf Posted on May 3, 2019 at 5:54 am

    what about the autism that vaccines cause

  54. Make Racists Afraid Again Posted on May 3, 2019 at 6:17 am

    Failing to fully Vaccinate kids is Child Abuse.
    No child has ever gotten Autism from a Vaccine.
    It has never happened.
    It doesn’t happen.
    It will never happen.
    Being religious is no excuse.
    Being uneducated is no excuse.
    Doctors actually know more than you do. Who are you going to believe, the entire scientific and medical communities or a handful of uneducated social media influencers who want to sell you something.
    Science doesn’t care what you believe and neither do microorganisms.
    Only Science matters.

  55. Sayan guria Posted on May 3, 2019 at 7:19 am

    So the virus uses unconventional warfare to fight our immune system

  56. Michael Frazier Posted on May 3, 2019 at 10:57 am

    Thought this was vox

  57. DippnDonuts Posted on May 3, 2019 at 11:30 am

    Do we actually have people that don’t like vaccines?

  58. Claire Wheeler Posted on May 3, 2019 at 11:50 am

    What happened to the shortened version of this video where it talks about the macrophage carrying the measles virus as it doesn't distinguish it as a foe? I was talking about dr bradstreets incredible work in helping over 600 children derive release from many of thier asd symptoms through helping the immune system see the virus for what it is.
    Some viruses and cancers use nagalase to hide the fact that thier cells are invaders by making the macrophage slow and a bit blind so they cant distinguish between a healthy and unhealthy cell. This stops them from destroying them. Many holistic doctors have researched this and I'm sorry to say that a fair few have died in nefarious circumstances. There is a question that the nagalase is going in to vaccines as those with autism and cancer have high levels of nagalase generally and it's not from birth. Therefore it is seen as possibly from inside the vaccines administered. Dr bradstreet was using gcmaf to wake the macrophage back up an extra 30% making them more efficient in eliminating mutant cells and alleviating symptoms.

  59. Boss Lax316 Posted on May 4, 2019 at 4:59 pm

    Thanks Antivaxers

  60. Claudio Rojas Posted on May 6, 2019 at 2:43 am

    Incredible what the media can do!
    No everyone is panicking about a benign childhood illness?
    Follow the money!
    Merck got You all by the balls!

  61. jackhappens Posted on May 7, 2019 at 1:55 am

    So measles acts like HIV and basically causes a condition similar to AIDS, and that's what kills people?

  62. Tirsa Heilbron Posted on May 7, 2019 at 7:16 pm

    This man has not seen the movie I’m legend it did not go well 😅

  63. Maelstrom Posted on May 9, 2019 at 2:02 am

    STOP TALKING TO ME LIKE I AM AN ANTI VAXXER! ffs, anti vaxxers are going extinct already so please stop making these stupid allusions everyone is an anti vaxxer ffs

  64. Angl0sax0nknight Posted on May 9, 2019 at 12:49 pm

    This another reason to control our borders! How many of those Illegals carry deadly diseases!! When it comes to the so called anti-vaccine people is not so much using vaccines but the chemicals that are used IN the vaccines. Why doesn’t anyone ask why the government gave BIG PHARM protection from people that get vaccines! The government has been paying out millions in TAXPAYERS money to those that were injured by vaccines. All one has to do is search it. It’s one of those dark secrets the Feds doesn’t want the public to know. Also research should be looked into the bodies reaction in children with the high vaccines count at one time. It might not effect 90% of the children but that 10% shouldn’t be disregarded.

  65. River Song Posted on May 9, 2019 at 1:54 pm

    When they mentioned they were trying to use measles to fight cancer all I was thinking was I am legend and now I’m scared

  66. Safir Posted on May 9, 2019 at 8:09 pm

    This is all propaganda from Big-Pharma. /s

  67. Safir Posted on May 9, 2019 at 8:10 pm

    Man, that annoying drumbeat makes me want to contract Measles.

  68. cc cav Posted on May 10, 2019 at 8:25 am

    I suffer from shingles. So whenever I have an outbreak, I casually walk through stores passing the virus… hahaha….

  69. mike ross Posted on May 12, 2019 at 1:05 am

    sure,.. has nothing to do with biologic warfare, or the toxic crap you call "food", or the straight up poison from the pharmacy.. yea its all from us anti vaxxers…. maybe detox yourselves and let your immune system get back to full strength.. fools..

  70. biiioya Posted on May 12, 2019 at 4:58 am

    I am pro-vax. But it doesn't seem reasonable to tell at a person, "hey, you wouldn't have those problems if you had just done what I told you to do," then expect them to listen to your explanation. Good information, just doesn't seem effective to attack people from the get-go, when they already have a fearful emotion toward the idea of vaccinations.

  71. Red Butterfly Posted on May 13, 2019 at 1:10 pm

    I want to inject letter S to this narrator..

  72. Jtzkb Posted on May 13, 2019 at 6:30 pm

    As I'm watching this, you keep assuming that people who have been vaccinated to not get measles. That is not accurate. Vaccines are highly effective, but they are not 100% effective. Even people who have been vaccinated can sometimes still get an uncontrolled infection.

  73. V I C T O R P A U L Posted on May 15, 2019 at 8:34 am

    Sick playlist is awesome plz make more videos ….I am a medical student it's very helpful to me and for medical student …. thanks

  74. PraiseY paraJustUS Posted on May 15, 2019 at 6:49 pm

    Youtube search "brady bunch measels."
    Or life search natural remedies for real life.

  75. farfett_il-lejl Posted on May 18, 2019 at 6:10 pm

    "if you haven't been vaccinated, maybe think about it"
    WHAT? Maybe think about it?! You should be isolated (preferably in prison) if you haven't been vaccinated

  76. farfett_il-lejl Posted on May 18, 2019 at 6:12 pm

    That last sentence, the one about using the measles virus to fight cancer is probably one of the most exciting things I've heard in quite some time

  77. Jenni Posted on May 21, 2019 at 2:45 pm

    Before vaccinating, ask what the preservatives are in the vaccine. Did everyone know most of our vacations are manufactured in China now?
    Yes, immunization is important. But please research about how they are poisoning certain vaccines. The DTP and Hep B vaccine is made with using fetal and placental tissue. Now there is a high incidence of girls having seizures and neurological issues after getting the Gaurdasil (HPV) Vaccines. My 17 year old daughter did about 10 minutes after receiving the vaccine.

  78. 1matttyler Posted on May 30, 2019 at 4:46 am

    Y’all should reach out to the Open Medicine Foundation and do an episode on ME/CFS

  79. Original Taboo Posted on June 2, 2019 at 6:05 am

    All the Karen’s are screaming out in pain right now, “BUT VACCINES CAUSE AUTISM!”

  80. Navneeth Lal Posted on June 15, 2019 at 2:10 pm

    I have an old enemy I would like to make into a new friend by genetically modifying him

  81. SgtHydra Posted on June 23, 2019 at 5:28 am

    Hilarious that this video implies that it is the intention of viruses like Measles to kill you. A virus has no intention or plan, least of all one to kill their host. Instead the virus just mucks around as it is programmed by its genes, and that mucking around does a lot of internal damage to the host. Some mucking around is more useful than other kinds, and thus evolution occurs. The most successful viruses 100% leave the host alive and infect the host on a yearly basis, aka the common cold.

  82. 1870 Preußen Posted on June 25, 2019 at 11:33 am

    0:38 German accent on another lvl

  83. dren % Posted on July 1, 2019 at 8:47 am

    I was vaccinated and i still caught measles

  84. Instant know Posted on July 3, 2019 at 10:18 am

    I like to watch new facts INSTA seeker.👍👍
    Will you make one video on 'AES' Acute Encephalitis Syndrome.

  85. dancingnature Posted on July 14, 2019 at 1:42 pm

    I caught measles as a 5 year old . They didn’t have a vaccine then . I remember how sick it made me. Why would any parents voluntarily put their child through that! Smh!

  86. dancingnature Posted on July 14, 2019 at 1:50 pm

    New York has a bad measles outbreak because of religious based antivaxxers . It’s 2019 . Still smh!

  87. Santiago Restrepo-Castillo Posted on July 16, 2019 at 3:03 pm

    I'm working with Dr. Cattaneo! u.u

  88. psiak ciapkowaty Posted on July 31, 2019 at 4:59 pm

    is it just me or does the narrator have a lisp

  89. v pai Posted on July 31, 2019 at 5:51 pm


  90. Super Nintendo MD from Hell Posted on August 6, 2019 at 2:41 pm

    This will be the rising of the T virus 🦠

  91. 404 Error Not Found Posted on August 21, 2019 at 10:49 pm

    The best way for a someone to handle an anti vaxer

    "Have you ever considered the fact that the Russians have spread propaganda to promote anti vaccination in an attempt to weaken the United States in preparation for invasion?"

    Just replace one conspiracy with another. If they are a Democrat add Trump to the sentence. If they are republican add Hillary to the sentence for extra effect.

  92. David Aspinall Posted on August 21, 2019 at 11:43 pm

    You also build an immunity by getting and defeating the virus – not only by vaccination.

    I am NOT advocating this as a means to develop immunity, just adding a fact that was omitted in this video.

  93. RomanoProductions Posted on August 22, 2019 at 3:16 am

    Make Measles Great Again

  94. noybw333 Posted on August 22, 2019 at 2:54 pm

    So am I understanding this right? -measles isn’t actually deadly, is can just make your immune system temporarily weaker so other things can kill you?

  95. Boom Jonggol Posted on August 22, 2019 at 3:03 pm

    Measles: sneaks onto macrophage
    Other immune cells when they finally realize: (speaks to macrophage) you have become the very thing you swore to destroy

  96. Jacob 1 Posted on August 23, 2019 at 2:20 pm

    What if you made it so when the virus dies it gives the host enhanced cognition? That would be cool

  97. Semper Fidelis Posted on September 12, 2019 at 10:52 pm

    So far 106 anti-vaxxers disliked this video.

  98. Andrew Cisneros Posted on September 13, 2019 at 7:25 pm

    This girl from my high school had a baby, she's a dumbass(anit-vaxer). I watch her posts on Instagram, waiting for the dead baby post.