April 2, 2020
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– There have been a lot of advances with the ketogenic diet and cancer. Now it’s important to
note, no matter what, that in no way shape
or form is this saying that the ketogenic diet
is going to cure cancer. But it’s important that people understand how cancer cells generally eat, but in order to understand
that we also have to understand how normal cells, non-cancer
cells actually eat. When I say eat I mean what
kind of things they consume, glucose, fat, how they breathe. What metabolic process they go through. So we’re going to break it all down, but I also want to highlight a 2019 study that is pretty fascinating in the world of cancer research and nutrition. My name’s Thomas DeLauer with Keto-Mojo and we’re going to dive in to
cellular metabolism and cancer. So first thing’s first, a
normal cell in our human body utilizes glucose and combines
it with oxygen to create what is known as ATP to create energy. When oxygen is not present, what happens is glucose still
combines with other processes, but it ultimately creates
lactic acid as a byproduct. Now why does this matter when
we’re talking about cancer? Cancer cells don’t do the same thing. Cancer cells take in glucose, and directly turn it into lactic acid. They do this simply because
they have a little bit of an impaired mitochondrial ability. What that means is, the mitochondria, the energy
powerhouse of the cancer cell is a little bit dysfunctional compared to that of a normal cell. It’s different, it’s mutant. A cancer cell in general
is kind of mutant right? Now what that means to us is that they need a
lot of glucose to grow. They need a lot of glucose to stay alive because they’re inefficient at
creating energy and growing. We often think that cancer
cells are very efficient and grow rapidly, they do on the surface
but as far as the energy that they need to grow, they actually are pretty inefficient. They take a lot of glucose
to have a little effect. The point is here is that
if we for the most part, do deprive ourselves of insulin
and glucose to some degree, a lot of cancer cell
growth ends up stopping. Now let’s also take a look
at something called insulin. Insulin is a signaling pathway. Insulin allows cells to grow, it is an anabolic hormone in
a sense, it is pro growth. In a normal cell it allows
glucose to come into the cell to grow, well it also does
that with tumors, with cancer. Insulin is a signaling pathway and if we can slow down the
insulin levels and lower those, then we won’t have as much
potential cancer growth. Again, I use these words
a little bit loosely because I want to make
sure that we’re not saying that this is the end all be all. What we have found through
lots of different research is that it is largely dependent
on the types of cancer. A lot of cancers respond very
very well to a ketogenic diet in the sense that they don’t grow anymore, and that’s simply because the cancer cells are so metabolically inefficient, they don’t know how to use
fats for fuel properly. Whereas the other cells
in our body can use fats and ketones, the cancer cells just can’t. So they end up staying stagnant
and sometimes even starving. So now let’s go ahead and
talk about this 2019 study because it’s pretty interesting stuff. So this study was published in the Journal Cell Reports in 2019. It took a look at squamous
cell lung cancers. So squamous cells are cancer
cells that we know know, really thrive on sugar. So in some ways, this study
was a little bit unfair because it already looked at
a cell that we already know responds well to sugar. But still really interesting stuff, because they found that a
ketogenic diet did stop the growth of a squamous cell cancer cell. Really wild stuff. And they also found that
if you were just to eat a regular diet with that, so in this case it was mice that were consuming
their normal chow diet, their chow diet’s just like almost like a standard American diet. So what’s interesting is the
standard American or chow diet, still caused the standard growth. So the cell was able to grow, the cancer cell was able to
grow and cancer went along. So interesting here is that we’re not finding a cure for cancer, but we are finding the
ketogenic diet could stop some kinds of cancers from growing, therefore allowing adjunct
treatments to do their job. Ketones are exceptionally important here because this is where it comes down to it, ketones like the things
that you’re measuring with your meter right here, the most important piece
of the ketogenic diet, they can’t be used as
fuel in a cancer cell, or most cancer cells,
because they lack the ability at the mitochondrial level. So you essentially starve it. So the same study took a
look at individuals, people, not mice, that had squamous cell lung and esophageal cancers. They found that once again,
there was a correlation between high levels of glucose
and squamous cell cancers. So showing that even lifestyle factors, just consuming more
sugar could be correlated with squamous cell cancers. Now correlation does not equal causation, but it’s important to note. But at the end of all of this, whether a cancer cell or a
regular cell can use sugar, fats or beta hydroxybutyrate, is a little bit irrelevant because we don’t know all the details yet. We’re still uncovering so
much, but what we do know, is at the end of all of this,
keeping our insulin levels low is what is super important. Because no matter what kind of cancer, if our insulin levels are high, we are triggering a pro-growth signal. We’re triggering a pro-growth signal that can cause a tumor to
grow, can cause a regular cell to grow, can cause a fat cell to grow. At the end of all of it, again, insulin is a problem if
we have too much of it. So we can at least table this to the sense of keeping your insulin
levels low gives you a fighting chance in a
lot of different ways. But the research is still
coming in at rapid light speed, proving that the ketogenic diet could be a really powerful
way to combat cancer. We’ll bring a lot more detail
on this as science unfolds, as we always want to keep you up to speed on the amazing advances
with the ketogenic diet and the medical community as well. So make sure you keep it
locked in here with Keto-Mojo and keep the guesswork out of the equation and leave that measuring of your ketones to the gold standard meter, and I’ll see you in the next video.

Randall Smitham