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The 5-2 Diet and the Fasting-Mimicking Diet Put to the Test


Randall Smitham

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58 COMMENTS

  1. Chris Namaste Posted on November 25, 2019 at 1:12 pm

    Ha ha first. 😉

    Reply
  2. CoMeBack pVi Posted on November 25, 2019 at 1:16 pm

    Liked the video before starting watching it 🙂

    Reply
  3. AnastasiaKara Posted on November 25, 2019 at 1:17 pm

    Always coming to Dr. Greger for advice:)

    Reply
  4. Donna Roberts Posted on November 25, 2019 at 1:22 pm

    Excellent information.

    Reply
  5. Arthritis to Athlete Posted on November 25, 2019 at 1:22 pm

    First, last, who cares?! I’m here for the science 😎👍🏼

    Reply
  6. Fools Gold Found Posted on November 25, 2019 at 1:25 pm

    I feel a bout of orthorexia coming on, where’s that broccoli?

    Reply
  7. Deen Truth Posted on November 25, 2019 at 1:27 pm

    Who can remember a diet like this? Does not come off practical to the ever increasing obese American population.

    Reply
  8. Madhav Manjunath Posted on November 25, 2019 at 1:33 pm

    Man your content is amazing, it's so pure, the number of dislikes say it all.. thanks for existing!

    Reply
  9. Luke Weaver Posted on November 25, 2019 at 1:36 pm

    Real (clean) greens, sprouts, sprouted seeds/nuts, herbs & veggies are where it's at…especially wild and home grown.

    Reply
  10. joe rogan eats bugs Posted on November 25, 2019 at 1:38 pm

    i wouldnt curse longo for selling a product, i trust his work in this field.

    Reply
  11. Dan Cagle Posted on November 25, 2019 at 1:40 pm

    Dr. Klaper advises a brief fast one day a month. I tend to think that eating WFPB  (with all the fiber) is a form of calorie restriction. In fact eating more calories may be necessary since high amounts of fiber block caloric uptake.

    Reply
  12. RipeApple Posted on November 25, 2019 at 1:45 pm

    I respect Valter Longo for his work in longevity science. And i would maybe try his product if he could prove that his "special ingredients" can be more benefitial then a regural calorie restriction. His claims are not only limited to weight loss, but also include faster regeneration, and slower aging. Can't wait to find out more.

    Reply
  13. Test Posted on November 25, 2019 at 1:56 pm

    I trust Dr. Longo‘s research & science. In his multiple interviews (the best with Rich Roll and Dr. Hymann) he explains the mimicking effect of this type of fasting and why he had chosen this type over plain water fasting. It was not designed with focus on weightloss or even kick-off a change of eating habits -although these were well appreciated side effects – but to support & intensify the treatment of cancer patients and induce cell rejuvenation. To ensure that and to make sure the low calorie & macro/micro nutrient mix is done absolutely perfectly he designed the package. You can recreate the food by yourself, in his book he explains the portfolio.

    Reply
  14. ooo789456123 Posted on November 25, 2019 at 2:01 pm

    Save the 50 USD per day, "DIY fasting mimicking diet": cooking a simple vegetable soup 🌽🍅🍆🍵and a few almonds or walnuts 🌰 plus herbal tea without anything added, first day 800 calories, 2nd to 5th day 500 calories per day. Don't do it if you're pregnant, diabetic etc. Ask your doctor!

    Reply
  15. Vegan Linked Posted on November 25, 2019 at 2:14 pm

    Really the best and most simple method for eating is found through the "daily dozen app" 🙂 Otherwise, the more you look the more complicated it most likely will seem that people are trying to make things. It always circles back around to the most simple things being the best, and that's just eating plant based whole foods. No calorie counting needed. No fasting. Maybe a little more planning ahead than just eating processed foods. And maybe a little discipline to not eat too late in the evening.

    Reply
  16. TheOneMastodon Posted on November 25, 2019 at 2:28 pm

    If anyone's interested, this idea isn't new or hard to do yourself. In fact, this is literally all over YouTube in the form of "weight loss cabbage soups" which are pretty much variations of some sort of stock, onions, cabbage, some spices and other low-calorie vegetables cooked in water for long periods of time. Have fun !

    Reply
  17. Noah97 Posted on November 25, 2019 at 2:40 pm

    How about fasting for autophagy. Is that a valid reason for fasting, and for who?

    Reply
  18. Alan Angel Posted on November 25, 2019 at 2:40 pm

    I find it easier to fast on the weekend because you can keep physically busy. Screw trying to fast sitting at a desk all day.

    Reply
  19. captquest1 Posted on November 25, 2019 at 2:46 pm

    I've been fasting two days a week (not consecutive) for 18 to 24 hours at a time. Been doing this for over five years now. I've always believed in the science studies showing it increases insulin sensitivity, and HGH. I like the idea of giving my digestive system a break and it's a good way to keep my weekly calorie intake at bay. Some times I'll exercise or cycle while fasting to get into a keto state (fat burning). I feel an increase in energy and mental clarity when I do this.

    Reply
  20. Eelke Aptroot Posted on November 25, 2019 at 2:49 pm

    I've tried the fasting mimicking diet myself a few times, to get rid of a tooth acke, worked like a charm. I did of course cook my own soup, after seeing the prices for those FMD packets.

    Reply
  21. King Fish Posted on November 25, 2019 at 2:54 pm

    It would affect my mood. Fact 🙂

    Reply
  22. Rabbit Food Fitness Posted on November 25, 2019 at 3:18 pm

    Thank you for this awesome video Dr.Greger. This video is awesome!

    Reply
  23. Danny Sargeant Posted on November 25, 2019 at 3:48 pm

    I’m on day 1 of a 5 day FMD diet. Meal 1 today: oatmeal with a little protein and coconut oil (500 cal). Meal 2: Pineapple and Vegetarian Chili (500 cal). This is my 8th time doing this protocol.

    Reply
  24. Joseph1NJ Posted on November 25, 2019 at 4:11 pm

    If I go more than 12 hours without calories, I "feel" like I'm hypoglycemic, even though I'm not. I get weak, shaky, tired, and even though I normally avoid added sugars, a few sips of a sugary soda, which I never drink, and I'm normal again until I eat.

    Reply
  25. Mike Skylark Posted on November 25, 2019 at 4:17 pm

    Any type of fasting on WHOLE FOOD VEGAN DIET (with supplements) is 100% unneccessary & potentialy dangerous! Been there, done that (unless your body fat % is higher than 20%).

    Reply
  26. Brandon Swan Posted on November 25, 2019 at 4:30 pm

    Just FYI to everyone. The FMD was not created for weight loss. It was created mostly as a supplementary treatment for cancer patients. Dr. Longo originally prescribed a 3 day (72 hour) fast prior to chemotherapy. Because the adherence rate was so low he developed a diet (5 days instead of 3) to mimic fasting to see if it could get the same benefits but with higher adherence.

    Reply
  27. m0L3ify Posted on November 25, 2019 at 4:51 pm

    It seems like the benefits seen here are the same as with a plant-based diet. Has anyone ever compared fasting to WFPB, head to head in the same study?

    Reply
  28. अष्टावक्रः ashtavakra Posted on November 25, 2019 at 5:26 pm

    bloatmeal… stay away from it.

    Reply
  29. samanjj Posted on November 25, 2019 at 5:36 pm

    For those having trouble making quick tasty veggies, may I recommend Chinese hot pot? I’ve never enjoyed eating simple plain vegetables so much.

    Reply
  30. Citizenthirteen Posted on November 25, 2019 at 6:07 pm

    I have a new diet . it's called the 7-0 , 24 hour diet . It's amazing , eat whatever you like and as much as long as it's whole foods that are plant based . No starvation , no fasting . No pain, no weight gain . I know it's shocking to the sadomasochistic stupid unsustainable diet people . SMH

    Reply
  31. Justus Stern Posted on November 25, 2019 at 6:17 pm

    "Oatmeal" is such a retarded word….

    Reply
  32. Rafael Birkner Posted on November 25, 2019 at 6:34 pm

    Perhaps constant caloric restriction is promoting weight loss, but real fasting it promoting body re-composition without a big weight loss – read lose fat but keep your active body tissue

    Reply
  33. Rex Buyeo Posted on November 25, 2019 at 8:13 pm

    Please talk about the new
    Martin-Hopkins Calculation for LDL .
    For some reason my entire family has awesome cholesterol levels now.

    Reply
  34. The King Posted on November 25, 2019 at 8:47 pm

    Definitively good to brew some tasty eating disorders.

    Reply
  35. Bob Schmob Posted on November 25, 2019 at 8:52 pm

    Finally covering this! Thank you!

    Reply
  36. Fabio Posted on November 25, 2019 at 9:00 pm

    Everyone needs an income to support themselves. Longo sells FMD eating plan and you sell books. Ive been intermittent fasting for 5 years now.  It works for me.

    Reply
  37. Bob Schmob Posted on November 25, 2019 at 9:07 pm

    What about the fiber content of the diet? What is the total fiber content? Perhaps this of importance? What about macros?

    Reply
  38. Julot Posted on November 25, 2019 at 10:31 pm

    Thats ridiculous.. and the soups are processed foods with oils, salt, and not even low fat at all apparently and there also are vitamins supplement which showed in many studies to be often useless and/or harmful… just do some real water fast for few days once in a while, will be much better, much more efficient and much cheaper, it will probably also be easier than eating a very low calories diet…

    Reply
  39. JadeMusic Posted on November 26, 2019 at 1:18 am

    Dr. Michael Mosley did a documentary with Longo a few years ago on the effects of a mimicking fasting diet. You can find it here on YouTube (I think it's something like, "Eat, Fast and Live Longer"). It's quite interesting, and it demonstrated how using the 5:2 approach, Mosley was able to improve his health and eliminate his (pre)diabetic state. Calorie restriction does have benefits.

    Reply
  40. Dave Forgot Posted on November 26, 2019 at 1:24 am

    This whole mimicking diet salesmanship is a scam. Baby doctor Longo is donating his salary but what about his stock options or other money that might be given to other parts of his Empire

    Reply
  41. IA9876 Posted on November 26, 2019 at 1:24 am

    To his credit Dr Longo gives instructions on how to do the fasting mimicking diet using plant based ingredients yourself rather than buying his five day meal plans so that anyone who wants to try it can do so with low cost whole food ingredients at home.

    Reply
  42. maremacd Posted on November 26, 2019 at 2:24 am

    Why the random LDL study at 1:56??? Were we talking about cholesterol???

    Reply
  43. Corellispinto Posted on November 26, 2019 at 2:31 am

    Dr. Greger really missed the mark on this one. The purpose of Dr. Longo’s FMD is to get the anti-aging effects of fasting (inhibition of mTor and promotion of autophagy, etc.) without actually fasting. Not everyone can safely water fast. It’s not a weight loss protocol. Dr. Longo’s longevity diet is a whole food plant based diet.

    Reply
  44. Isaac Guedes Posted on November 26, 2019 at 2:42 am

    Fast mimicking diet helps old people, Who uses medicine pills, and cant water fast. Do what you can. Just fast, water or fast mimicking diet

    Reply
  45. a a Posted on November 26, 2019 at 3:58 am

    Dr can you please elaborate more on the autophagy aspect of fasting. Also if there's anything in regards to healthy to athletic people fasting eating in a 12 to 20 hour eating window daily?

    Reply
  46. May Ploy Posted on November 26, 2019 at 9:06 am

    REAL VEGETABLES…Ding ding ding 🎶

    Reply
  47. The Artificial Society Posted on November 26, 2019 at 10:15 am

    The FMD study did not use people that are really healthy eaters already. Any diet that cuts saturated fat and animal protein is going to have positive effects. If you give FMD to really whole plant food eaters, the will be no benefit and maybe harm.

    Reply
  48. Saved By Grace Posted on November 26, 2019 at 4:40 pm

    Seems the cabbage soup diet would attain the same results. Not many calories in cabbage soup.

    Reply
  49. Lukas Mena Posted on November 26, 2019 at 4:54 pm

    Hi dr. Greger do you know any good master degree in plant based nutrition?

    Reply
  50. hyevoltage Posted on November 26, 2019 at 5:11 pm

    Valter Longo has answered the last question of this video in various interviews he's done. He said that the exact formulation and ratios of the macro & micro nutrient composition is important and easy to get wrong if doing it on your own. He also said there are certain key ingredients, like the glycerin in the Prolon L-Drink that people may not know of which helps the fasting process and prevents problems.

    To be honest, I don't think he makes a convincing case against most pro-active health-conscious people figuring this out themselves from regular food they can buy at the grocery store, however, we all hear funny customer support stories of clueless people doing the most insane things thinking they're following the correct directions, so if absolute compliance is needed, such as in clinical settings, then he is right to want to standardize and package the food to make things as fool proof as possible for patients. He has told anecdotes of several patients who fasted themselves to death while thinking they were following protocol.

    Reply
  51. Steve T Posted on November 27, 2019 at 3:39 pm

    Related to Dr. Longo's FMD product, Prolon, I purchased one "kit" , and followed the FMD for the 5 days. After that, I did what you suggested: I designed my own diet to match Prolon's nutritional profile using salads, soups, and nuts, algae based omega-3 and multi-vitamin supplements. I did that 5 day FMD for another 2 cycles.

    Reply
  52. iamgoddard Posted on November 27, 2019 at 5:30 pm

    One-day fast per week is what I've been doing for some time. Unexpectedly, I feel very little hunger on day two when I break my fast usually many hours after I've woken up. So day two might actually be easier than day one, perhaps. I'll try it out and see!

    Another curious thing I've noticed is I can be really hungry on other days, but on my regular scheduled fasting day, I usually experience almost no hunger. It's as if my body knows what's up and so dials back the hunger pangs.

    Reply
  53. john doe Posted on November 27, 2019 at 6:31 pm

    on a FMD you get 45% cals from carbs, 45% from fat, and only 10% protein. this is precise, because high-ish fat and little calories will get you into ketosis, which is the main purpose of fmd.

    Reply
  54. Impolite Vegan Posted on November 28, 2019 at 12:49 am

    Doc, go to Rogans podcast and destroy the bs spreader please

    Reply
  55. Jennifer Stokes Posted on November 28, 2019 at 12:43 pm

    Dr. Longo's research is really interesting.

    Reply
  56. Galliano Marr Posted on November 30, 2019 at 2:09 pm

    I dont quite get this, is it good to do the 2 Days fast or not?

    Reply
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